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Disappointing results from malaria vaccine trial

Everyone involved in malaria control has a fervent wish a malaria vaccine is found.
 
Recent results from an ongoing trial are therefore disappointing.
 
The trial’s report concludes: ‘The efficacy of RTS,S/AS01E vaccine over the 4-year period was 16.8%. Efficacy declined over time and with increasing malaria exposure.’
 
Reuters reports: ‘The disappointing results for RTS,S - the world's first potential malaria vaccine - raise further questions about whether it can make a difference in the fight against the disease, a major cause of illness and death among children in sub-Saharan Africa. "The results are kind of disappointing because we'd all like to see a malaria vaccine that has closer to 80 percent or 100 percent efficacy," said Christopher Plowe, a malaria researcher at the University of Maryland School of Medicine in the United States, who was not involved in the RTS,S trial. There is currently no vaccine that offers complete protection against malaria. Control measures such as insecticide-treated bednets, indoor spraying and anti-malaria drugs have helped cut malaria cases and deaths significantly in recent years, but drug resistance is growing and experts say an effective vaccine could be a vital tool in eradicating the disease.’